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Striker Neurovascular PRODUCTOS


20 enero 2021

Good Clinical Outcome Decreases With Number of Retrieval Attempts in Stroke Thrombectomy

Fabian Flottmann, Caspar Brekenfeld, Gabriel Broocks, Hannes Leischner, Rosalie McDonough, Tobias D. Faizy, Milani Deb-Chatterji, Anna Alegiani, Götz Thomalla, Anastasios Mpotsaris, Christian H. Nolte, Jens Fiehler and Máté E. Maros

Abstract Background and Purpose: Endovascular therapy is the standard of care in the treatment of acute ischemic stroke due to large-vessel occlusion. Often, more than one retrieval attempt is needed to achieve reperfusion. We aimed to quantify the influence of endovascular therapy on clinical outcome depending on the number of retrievals needed for successful reperfusion in a large multi-center cohort.

12 enero 2021

Stroke Imaging Selection Modality and Endovascular Therapy Outcomes in the Early and Extended Time Windows

Raul G. Nogueira, Diogo C. Haussen, David Liebeskind, Tudor G. Jovin, Rishi Gupta, Ashutov Jadhav, Ron F. Budzik, Blaise Baxter, Antonin Krajina, Alain Bonafe, Ali Malek, Ana Paula Narata, Ryan Shields, Yanchang Zhang, Patricia Morgan, Bruno Bartolini, Joey English, Michael R. Frankel, Erol Veznedaroglu and for the Trevo Registry and DAWN Trial Investigators

Abstract Background and Purpose: Advanced imaging has been increasingly used for patient selection in endovascular stroke therapy. The impact of imaging selection modality on endovascular stroke therapy clinical outcomes in extended time window remains to be defined. We aimed to study this relationship and compare it to that noted in early-treated patients.

12 enero 2021

Excess Cerebrovascular Mortality in the United States During the COVID-19 Pandemic

Richa Sharma, Lindsey R. Kuohn, Daniel M. Weinberger, Joshua L. Warren, Lauren H. Sansing, Adam Jasne, Guido Falcone, Amar Dhand and Kevin N. Sheth

Abstract Background and Purpose: The magnitude and drivers of excess cerebrovascular-specific mortality during the coronavirus disease 2019 (COVID-19) pandemic are unknown. We aim to quantify excess stroke-related deaths and characterize its association with social distancing behavior and COVID-19–related vascular pathology.

11 enero 2021

Cost-Effectiveness of Mechanical Thrombectomy for Treatment of Nonminor Ischemic Stroke Across Europe

Paolo Candio, Mara Violato, Jose Leal and Ramon Luengo-Fernandez

Abstract Background and Purpose: Mechanical thrombectomy (MT) has been recommended for the treatment of nonminor ischemic stroke by national and international guidelines, but cost-effectiveness evidence has been generated for only a few countries using heterogeneous evaluation methods. We estimate the cost-effectiveness of MT across 32 European countries.

08 enero 2021

CD31 Mimetic Coating Enhances Flow Diverting Stent Integration into the Arterial Wall Promoting Aneurysm Healing

Jonathan Cortese, Charlotte Rasser, Guillaume Even, Sylvia M. Bardet, Christine Choqueux, Jules Mesnier, Marie-Laure Perrin, Kevin Janot, Jildaz Caroff, Antonino Nicoletti, Jean-Baptiste Michel, Laurent Spelle, Giuseppina Caligiuri and Aymeric Rouchaud

Background and Purpose: Beyond aneurysmal occlusion, metallic flow diverters (FDs) can induce an adverse endovascular reaction due to the foreignness of metal devices, hampering FD endothelialization across the aneurysm neck, and arterial healing of intracranial aneurysms. Here, we evaluated the potential benefits of an FD coating mimicking CD31, a coreceptor critically involved in endothelial function and endovascular homeostasis, on the endothelialization of FDs implanted in vivo.

07 diciembre 2020

Acute Cerebrovascular Events With COVID-19 Infection

Mandip S. Dhamoon, Alison Thaler, Kapil Gururangan, Amit Kohli, Daniella Sisniega, Danielle Wheelwright, Connor Mensching, Johanna T. Fifi, Michael G. Fara, Nathalie Jette, Ella Cohen, Priya Dave, Aislyn C. DiRisio, Jonathan Goldstein, Emma M. Loebel, Naomi A. Mayman, Akarsh Sharma, Daniel S. Thomas, Ruben D. Vega Perez, Mark R. Weingarten, Huei Hsun Wen, Stanley Tuhrim and Laura K. Stein

Abstract Background and Purpose: Coronavirus disease 2019 (COVID-19) has been associated with an increased incidence of thrombotic events, including stroke. However, characteristics and outcomes of COVID-19 patients with stroke are not well known.

30 noviembre 2020

Influence of the COVID-19 Pandemic on Treatment Times for Acute Ischemic Stroke

James E. Siegler, Alicia M. Zha, Alexandra L. Czap, Santiago Ortega-Gutierrez, Mudassir Farooqui, David S. Liebeskind, Shashvat M. Desai, Ameer E. Hassan, Amy K. Starosciak, Italo Linfante, Vivek Rai, Jesse M. Thon, Ryna Then, Mark E. Heslin, Lauren Thau, Priyank Khandelwal, Mahmoud H. Mohammaden, Diogo C. Haussen, Raul G. Nogueira, Dinesh V. Jillella, Fadi Nahab, Artem Kaliaev, Thanh N. Nguyen, Osama Zaidat, Tudor G. Jovin and Ashutosh P. Jadhav

Background and Purpose: The pandemic caused by the novel coronavirus disease 2019 (COVID-19) has led to an unprecedented paradigm shift in medical care. We sought to evaluate whether the COVID-19 pandemic may have contributed to delays in acute stroke management at comprehensive stroke centers.

07 diciembre 2020

Early Infarct Growth Rate Correlation With Endovascular Thrombectomy Clinical Outcomes

Amrou Sarraj, Ameer E. Hassan, James Grotta, Spiros Blackburn, Arthur Day, Michael Abraham, Clark Sitton, Mark Dannenbaum, Chunyan Cai, Deep Pujara, William Hicks, Nirav Vora, Ronald Budzik, Faris Shaker, Ashish Arora, Roy F. Riascos, Haris Kamal, Sheryl Martin-Schild, Maarten Lansberg, Rishi Gupta, Gregory W. Albers and for the SELECT Investigators

Abstract Background and Purpose: Time elapsed from last-known well (LKW) and baseline imaging results are influential on endovascular thrombectomy (EVT) outcomes.

22 diciembre 2022

Utility of Severity-Based Prehospital Triage for Endovascular Thrombectomy

Henry Zhao, Karen Smith, Stephen Bernard, Michael Stephenson, Henry Ma, Ronil V. Chandra, Thanh Phan, Christopher F. Bladin, Leonid Churilov, Douglas Crompton, Helen M. Dewey, Tissa Wijeratne, Geoffrey Cloud, Vincent Thijs, Timothy J. Kleinig, Jo Lyn Ng, Cameron Williams, Fana Alemseged, Felix Ng, Peter J. Mitchell, Mark W. Parsons, Nawaf Yassi, Stephen M. Davis and Bruce C.V. Campbell

Abstract Background and Purpose: Severity-based assessment tools may assist in prehospital triage of patients to comprehensive stroke centers (CSCs) for endovascular thrombectomy (EVT), but criticisms regarding diagnostic inaccuracy have not been adequately addressed. This study aimed to quantify the benefits and disadvantages of severity-based triage in a large real-world paramedic validation of the Ambulance Clinical Triage for Acute Stroke Treatment (ACT-FAST) algorithm.

22 diciembre 2022

Importance of Occlusion Site for Thrombectomy Technique in Stroke

Marie Louise E. Bernsen, Robert-Jan B. Goldhoorn, Hester F. Lingsma, Robert J. van Oostenbrugge, Wim H. van Zwam, Maarten Uyttenboogaart, Yvo B.W.E.M. Roos, Jasper M. Martens and Jeannette Hofmeijer

Abstract Background and Purpose: Thrombectomy with stent retriever and direct aspiration are equally effective in the endovascular treatment of anterior circulation acute ischemic stroke. We report efficacy and safety of initial treatment technique per occlusion segment.

22 diciembre 2020

Mismatch Profile Influences Outcome After Mechanical Thrombectomy

Jean-Marc Olivot, Jean-François Albucher, Adrien Guenego, Claire Thalamas, Michael Mlynash, Vanessa Rousseau, Amel Drif, Soren Christensen, Agnes Sommet, Alain Viguier, Jean Darcourt, Lionel Calvière, Patrice Menegon, Nicolas Raposo, Anne-Christine Januel, Fabrice Bonneville, Thomas Tourdias, Mikael Mazighi, Igor Sibon, Gregory W. Albers and Christophe Cognard

Background and Purpose: Mechanical thrombectomy (MT) is the recommended treatment for acute ischemic stroke caused by anterior circulation large vessel occlusion. However, despite a high rate of reperfusion, the clinical response to successful MT remains highly variable in the early time window where optimal imaging selection criteria have not been established. We hypothesize that the baseline perfusion imaging profile may help forecast the clinical response to MT in this setting.

11 diciembre 2020

Bridging Thrombolysis Achieved Better Outcomes Than Direct Thrombectomy After Large Vessel Occlusion

Yuting Wang, Xiao Wu, Chengcheng Zhu, Mahmud Mossa-Basha and Ajay Malhotra

Abstract The utility and necessity of pretreatment with intravenous thrombolysis (IVT) before mechanical thrombectomy (MT) remains an issue of strong debate. This study aims to compare the outcomes of bridging thrombolysis (BT, IVT+MT) with direct MT (d-MT) after large vessel ischemic stroke based on the most up-to-date evidence. MEDLINE, EMBASE, Scopus, and the Cochrane Library from January 2017 to June 2020 were searched for studies that directly compared the outcomes of the 2 strategies. Methodological quality was assessed using the Quality in Prognostic Studies tool. Combined estimates of odds ratios (ORs) of BT versus d-MT were derived. Multiple subgroup analyses were performed, especially for IVT-eligible patients. Thirty studies involving 7191 patients in the BT group and 4891 patients in the d-MT group were included. Methodological quality was generally high. Compared with patients in the d-MT group, patients in the BT group showed significantly better functional independence (modified Rankin Scale score 0–2) at 90 days (OR=1.43 [95% CI, 1.28–1.61]), had lower mortality at 90 days (OR=0.67 [95% CI, 0.60–0.75]), and achieved higher successful recanalization (modified Thrombolysis in Cerebral Ischemia score 2b-3) rate (OR=1.23 [95% CI, 1.07–1.42]). No significant difference was detected in the occurrence of symptomatic intracranial hemorrhage between 2 groups (OR=1.01 [95% CI, 0.86–1.19]). Subgroup analysis showed that functional independence frequency remained significantly higher in BT group regardless of IVT eligibility or study design. Compared with d-MT, bridging with IVT led to better clinical outcomes, lower mortality at 90 days, and higher successful recanalization rates, without increasing the risk of near-term hemorrhagic complications. The benefits of BT based on this most recent literature evidence support the current guidelines of using BT.

04 diciembre 2020

Cerebral Venous Thrombosis

Jori O. Ruuskanen, Ville Kytö, Jussi P. Posti, Päivi Rautava and Jussi O.T. Sipilä

Abstract Background and Purpose: Epidemiology of cerebral venous thrombosis (CVT) has been reported to be changing. Because long-term nationwide data are needed to confirm this, we studied CVT occurrence between 2005 and 2014 in Finland

30 noviembre 2020

Leptomeningeal Collateral Flow Modifies Endovascular Treatment Efficacy on Large-Vessel Occlusion Strokes

Álvaro García-Tornel, Ludovico Ciolli, Marta Rubiera, Manuel Requena, Marian Muchada, Jorge Pagola, David Rodriguez-Luna, Matias Deck, Jesus Juega, Noelia Rodríguez-Villatoro, Sandra Boned, Marta Olivé-Gadea, Estela Sanjuan, Alejandro Tomasello, Carlos Piñana, David Hernández, José Álvarez-Sabin, Carlos A. Molina and Marc Ribó

Abstract Background and Purpose: We aim to evaluate if good collateral flow (CF) modifies endovascular therapy (EVT) efficacy on large-vessel stroke. To do that, we used final degree of reperfusion and number of device-passes performed, factors previously associated with better functional outcome, as main outcome measures.

06 febrero 2019

Real-World Treatment Trends in Endovascular Stroke Therapy

Hamidreza Saber, Babak B. Navi, James C. Grotta, Hooman Kamel, Arvind Bambhroliya, Farhaan S. Vahidy, Peng Roc Chen, Spiros Blackburn, Sean I. Savitz, Louise McCullough and Sunil A. Sheth

Abstract Background and Purpose— Recent landmark trials provided overwhelming evidence for effectiveness of endovascular stroke therapy (EST). Yet, the impact of these trials on clinical practice and effectiveness of EST among lower volume centers remains poorly characterized. Here, we determine population-level patterns in EST performance in US hospitals and compare EST outcomes from higher versus lower volume centers.

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