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01 noviembre 2017

RADIOLOGY. Imaging Neoadjuvant Therapy Response in Breast Cancer

Amy M. Fowler, David A. Mankoff, Bonnie N. Joe

The use of neoadjuvant systemic therapy in the treatment of breast cancer patients is increasing beyond the scope of locally advanced disease. Imaging provides important information in assessing response to therapy as a complement to conventional tumor measurements via physical examination. The purpose of this article is to discuss the advantages and limitations of current assessment methods, as well as review functional and molecular imaging approaches being investigated as emerging techniques for evaluating neoadjuvant therapy response for patients with primary breast cancer.

01 diciembre 2016

RADIOLOGY. Underestimation Rate at MR Imaging–guided Vacuum-assisted Breast Biopsy: A Multi-Institutional Retrospective Study of 1509 Breast Biopsies

Cécile Verheyden, Emma Pages-Bouic, Corinne Balleyguier, Pascal Cherel, Domenico Lepori, Guillaume Laffargue, Isabelle Doutriaux, Aurélie Jalaguier, Edouard Poncelet, Ingrid Millet, Isabelle Thomassin-Naggara, Patrice Taourel

Purpose: To assess the rate of underestimation of atypical ductal hyperplasia (ADH) and ductal carcinoma in situ (DCIS) at magnetic resonance (MR) imaging–guided vacuum-assisted breast biopsy and to explore the imaging, demographic, and histologic characteristics associated with lesion upgrade after surgery.

01 diciembre 2016

RADIOLOGY. Radiofrequency Ablation, MR Thermometry, and High-Spatial-Resolution MR Parametric Imaging with a Single, Minimally Invasive Device

M. Arcan Ertürk, Shashank Sathyanarayana Hegde, Paul A. Bottomley

Purpose: To develop and demonstrate in vitro and in vivo a single interventional magnetic resonance (MR)–active device that integrates the functions of precise identification of a tissue site with the delivery of radiofrequency (RF) energy for ablation, high-spatial-resolution thermal mapping to monitor thermal dose, and quantitative MR imaging relaxometry to document ablation-induced tissue changes for characterizing ablated tissue.

01 noviembre 2016

RADIOLOGY. Hepatocellular Carcinoma: Intra-arterial Delivery of Doxorubicin-loaded Hollow Gold Nanospheres for Photothermal Ablation—Chemoembolization Therapy in Rats

Junjie Li, Min Zhou, Fengyong Liu, Chiyi Xiong, Wanqin Wang, Qizhen Cao, Xiaoxia Wen, J. David Robertson, Xin Ji, Y. Andrew Wang, Sanjay Gupta, Chun Li

Purpose: To determine if combretastatin A-4 phosphate disodium (CA4P) can enhance the tumor uptake of doxorubicin (Dox)-loaded, polyethylene glycol (PEG)–coated hollow gold nanospheres (HAuNS) mixed with ethiodized oil for improved photothermal ablation (PTA)–chemoembolization therapy (CET) of hepatocellular carcinoma (HCC) in rats.

01 noviembre 2016

RADIOLOGY. Aldosterone-producing Adenoma in Primary Aldosteronism: CT-guided Radiofrequency Ablation—Long-term Results and Recurrence Rate

Shirley Yuk Wah Liu, Charmant Cheuk Man Chu, Teresa Kam Chi Tsui, Simon Kin Hung Wong, Alice Pik Shan Kong, Philip Wai Yan Chiu, Francis Chun Chung Chow, Enders Kwok Wai Ng

Purpose: To evaluate the long-term biochemical, clinical, and recurrence outcomes of radiofrequency (RF) ablation in treating primary aldosteronism due to aldosterone-producing adenoma (APA).

01 octubre 2016

RADIOLOGY. Endovascular MR-guided Renal Embolization by Using a Magnetically Assisted Remote-controlled Catheter System

Prasheel V. Lillaney, Jeffrey K. Yang, Aaron D. Losey, Alastair J. Martin, Daniel L. Cooke, Bradford R. H. Thorne, David C. Barry, Andrew Chu, Carol Stillson, Loi Do, Ronald L. Arenson, Maythem Saeed, Mark W. Wilson, Steven W. Hetts

Purpose: To assess the feasibility of a magnetically assisted remote-controlled (MARC) catheter system under magnetic resonance (MR) imaging guidance for performing a simple endovascular procedure (ie, renal artery embolization) in vivo and to compare with x-ray guidance to determine the value of MR imaging guidance and the specific areas where the MARC system can be improved.

01 octubre 2016

RADIOLOGY. Predictors of Clinical Outcome after Prostate Artery Embolization with Spherical and Nonspherical Polyvinyl Alcohol Particles in Patients with Benign Prostatic Hyperplasia

Tiago Bilhim, João Pisco, José A. Pereira, Nuno Vasco Costa, Lúcia Fernandes, Luís Campos Pinheiro, Marisa Duarte, António G. Oliveira

Purpose: To assess predictors of outcome after prostate artery embolization (PAE) for benign prostatic hyperplasia with spherical particle polyvinyl alcohol (sPVA) and compare outcomes with the use of nonspherical particle polyvinyl alcohol (nsPVA).

01 septiembre 2016

RADIOLOGY. Management of Uterine Fibroids: A Focus on Uterine-sparing Interventional Techniques

James E. Silberzweig, Daniel K. Powell, Alan H. Matsumoto, James B. Spies

Uterine fibroids occur in approximately 50% of women over the age of 40 years, and an estimated 50% of those are symptomatic. Menorrhagia is the most common symptom and the primary indication for treatment, although bulk symptoms often occur and can be treated. Pharmacotherapy is typically inadequate unless it can be expected to successfully bridge to menopause or allow for a less-invasive intervention. However, hormonal therapies have risks. Hysterectomy is still the most commonly performed procedure for symptomatic fibroids and has the lowest rate of reintervention (compared with myomectomy or uterine artery embolization [UAE]), but rates of more serious complications are higher and patient satisfaction and ability to return to normal activities may also be less favorable. Myomectomy is not necessarily less morbid than hysterectomy and may have a greater failure rate than UAE. Techniques and devices vary with little standardization, and operator experience is crucial to success. The largest studies of UAE show very low rates of serious complications and rapid recovery. UAE significantly improves symptoms related to uterine fibroids in 85%–90% of patients. Herein, this article will discuss the nature of fibroids and their diagnosis, pharmacotherapy, surgical treatment, and nonsurgical interventional treatment, including UAE and magnetic resonance–guided focused ultrasound.

01 septiembre 2016

RADIOLOGY. Colorectal Cancer Liver Metastases: Biopsy of the Ablation Zone and Margins Can Be Used to Predict Oncologic Outcome

Vlasios S. Sotirchos, Lydia M. Petrovic, Mithat Gönen, David S. Klimstra, Richard K. G. Do, Elena N. Petre, Alessandra R. Garcia, Afsar Barlas, Joseph P. Erinjeri, Karen T. Brown, Anne M. Covey, William Alago, Lynn A. Brody, Ronald P. DeMatteo, Nancy E. Kemeny, Stephen B. Solomon, Katia O. Manova-Todorova, Constantinos T. Sofocleous

Purpose: To establish the prognostic value of biopsy of the central and marginal ablation zones for time to local tumor progression (LTP) after radiofrequency (RF) ablation of colorectal cancer liver metastasis (CLM).

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