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ABSTRACT


15 febrero 2018

INTERNATIONAL JOURNAL OF CARDIOLOGY. Prognostic significance of QRS fragmentation and correlation with infarct size in patients with anterior ST-segment elevation myocardial infarction treated with percutaneous coronary intervention: Insights from the INFUSE-AMI trial

Björn Redfors, Ioanna Kosmidou, Aaron Crowley, Akiko Maehara, Ori Ben-Yehuda, Arslan Arif, José M. Dizon, Gary S. Mintz, Gregg W. Stone

Background: QRS fragmentation (fQRS) is believed to reflect myocardial scar formation in patients with coronary disease. Whether early formation of fQRS in patients with ST-segment elevation myocardial infarction (STEMI) treated with percutaneous coronary intervention (PCI) is correlated with infarct size and prognosis is unknown. We assessed the prognostic value of fQRS at 60 min post-PCI and its correlation with infarct size in patients with anterior STEMI managed with primary PCI.

01 noviembre 2017

AMERICAN HEART JOURNAL. Rationale of a novel study design for the BIOFLOW V study, a prospective, randomized multicenter study to assess the safety and efficacy of the Orsiro sirolimus-eluting coronary stent system using a Bayesian approach

Gheorghe Doros PhD, Joseph M. Massaro PhD, David E. Kandzari MD, Ron Waksman MD, Jacques J. Koolen MD, Donald E. Cutlip MD, Laura Mauri MD, MSC

Background: Traditional study design submitted to the Food and Drug Administration to test newer drug-eluting stents (DES) for marketing approval is the prospective randomized controlled trial. However, several DES have extensive clinical data from trials conducted outside the United States that have led to utilization of a novel design using the Bayesian approach. This design was proposed for testing DES with bioresorbable polymer compared with DES most commonly in use today that use durable polymers for drug elution.

01 enero 2018

JACC: CARDIOVASCULAR INTERVENTIONS. Effects of Body Mass Index on Clinical Outcomes in Female Patients Undergoing Percutaneous Coronary Intervention With Drug-Eluting Stents

Michela Faggioni, Usman Baber, Arash Ehteshami Afshar, Gennaro Giustino, Samantha Sartori, Sabato Sorrentino, Philippe G. Steg, Giulio G. Stefanini, Stephan Windecker, Martin B. Leon, Gregg W. Stone, William Wijns, Patrick W. Serruys, Marco Valgimigli, Edoardo Camenzind, Giora Weisz, Pieter C. Smits, David E. Kandzari, Soren Galatius, Clemens Von Birgelen, Raban V. Jeger, Ghada W. Mikhail, Dipti Itchhaporia, Laxmi Mehta, Rebecca Ortega, Hyo-Soo Kim, Adnan Kastrati, Alaide Chieffo, George D. Dangas, Marie-Claude Morice and Roxana Mehran

Objectives: This study sought to investigate the effect of different body mass index (BMI) categories on clinical outcomes in female patients treated with percutaneous coronary intervention (PCI) and drug-eluting stents.

01 enero 2018

JACC: CARDIOVASCULAR INTERVENTIONS. Effect of Increasing Stent Length on 3-Year Clinical Outcomes in Women Undergoing Percutaneous Coronary Intervention With New-Generation Drug-Eluting Stents

Jaya Chandrasekhar, Usman Baber, Samantha Sartori, Giulio G. Stefanini, Michele Sarin, Birgit Vogel, Serdar Farhan, Edoardo Camenzind, Martin B. Leon, Gregg W. Stone, Patrick W. Serruys, William Wijns, Philippe G. Steg, Giora Weisz, Alaide Chieffo, Adnan Kastrati, Stephan Windecker, Marie-Claude Morice, Pieter C. Smits, Clemens von Birgelen, Ghada W. Mikhail, Dipti Itchhaporia, Laxmi Mehta, Hyo-Soo Kim, Marco Valgimigli, Raban V. Jeger, Takeshi Kimura, Søren Galatius, David Kandzari, George Dangas and Roxana Mehran

Objectives: The aim of this study was to examine whether stent length per patient and stent length per lesion are negative markers for 3-year outcomes in women following percutaneous coronary intervention (PCI) with new-generation drug-eluting stents (DES).

01 enero 2018

JACC: CARDIOVASCULAR INTERVENTIONS. Impact of Sex on Comparative Outcomes of Radial Versus Femoral Access in Patients With Acute Coronary Syndromes Undergoing Invasive Management: Data From the Randomized MATRIX-Access Trial

Giuseppe Gargiulo, Sara Ariotti, Pascal Vranckx, Sergio Leonardi, Enrico Frigoli, Nestor Ciociano, Carlo Tumscitz, Francesco Tomassini, Paolo Calabrò, Stefano Garducci, Gabriele Crimi, Giuseppe Andò, Maurizio Ferrario, Ugo Limbruno, Bernardo Cortese, Paolo Sganzerla, Alessandro Lupi, Filippo Russo, Roberto Garbo, Arturo Ausiello, Dennis Zavalloni, Gennaro Sardella, Giovanni Esposito, Andrea Santarelli, Simone Tresoldi, Marco Stefano Nazzaro, Antonio Zingarelli, Anna Sonia Petronio, Stephan Windecker, Bruno R. da Costa and Marco Valgimigli

Objectives: This study sought to assess whether transradial access (TRA) compared with transfemoral access (TFA) is associated with consistent outcomes in male and female patients with acute coronary syndrome undergoing invasive management.

01 enero 2018

JACC: CARDIOVASCULAR INTERVENTIONS. Long-Term Outcomes With Transcatheter Aortic Valve Replacement in Women Compared With Men: Evidence From a Meta-Analysis

Marwan Saad, Ramez Nairooz, Naga Venkata K. Pothineni, Ahmed Almomani, Swathi Kovelamudi, Partha Sardar, Marcelo Katz, Mohamed Abdel-Wahab, Sripal Bangalore, Neal S. Kleiman, Peter C. Block and J. Dawn Abbott

Objectives: This study sought to examine long-term outcomes with transcatheter aortic valve replacement (TAVR) in women versus men.

01 enero 2018

JACC: CARDIOVASCULAR INTERVENTIONS. Sex-Specific Outcomes of Transcatheter Aortic Valve Replacement With the SAPIEN 3 Valve

Molly Szerlip, Sarah Gualano, Elizabeth Holper, John J. Squiers, Jonathon M. White, Darshan Doshi, Mathew R. Williams, Rebecca T. Hahn, John G. Webb, Lars G. Svensson, Ajay J. Kirtane, David J. Cohen, Pamela S. Douglas, Maria C. Alu, Aaron Crowley, E. Murat Tuzcu, Raj R. Makkar, Howard C. Herrmann, Vasilis Babaliaros, Vinod H. Thourani, Martin B. Leon, Susheel K. Kodali and Michael J. Mack

Objectives: The purpose of this study was to identify sex-specific outcomes of intermediate risk patients undergoing transcatheter aortic valve replacement with the SAPIEN 3 valve.

01 enero 2018

JACC: CARDIOVASCULAR INTERVENTIONS. Predictors and Clinical Outcomes of Next-Day Discharge After Minimalist Transfemoral Transcatheter Aortic Valve Replacement

Norihiko Kamioka, John Wells, Patricia Keegan, Stamatios Lerakis, Jose Binongo, Frank Corrigan, Jose Condado, Ateet Patel, Jessica Forcillo, Leslie Ogburn, Andy Dong, Hope Caughron, Amy Simone, Bradley Leshnower, Chandan Devireddy, Kreton Mavromatis, Robert Guyton, James Stewart, Vinod Thourani, Peter C. Block and Vasilis Babaliaros

Objectives: This study sought to investigate predictors and safety of next-day discharge (NDD) after transcatheter aortic valve replacement (TAVR).

01 enero 2018

JACC: CARDIOVASCULAR INTERVENTIONS. Importance of Contrast Aortography With Lotus Transcatheter Aortic Valve Replacement

Lennart van Gils, Jochen Wöhrle, David Hildick-Smith, Sabine Bleiziffer, Daniel J. Blackman, Mohamed Abdel-Wahab, Ulrich Gerckens, Stephen Brecker, Vinayak Bapat, Thomas Modine, Osama I. Soliman, Andrey Nersesov, Dominic Allocco, Volkmar Falk and Nicolas M. Van Mieghem

Objectives: The aim of this post hoc analysis from the RESPOND (Repositionable Lotus Valve System–Post-Market Evaluation of Real World Clinical Outcomes) post-market study was to assess the final implantation depth on the contrast aortogram after Lotus valve (Boston Scientific, Marlborough, Massachusetts) transcatheter aortic valve replacement (TAVR) and to correlate with permanent pacemaker implantation (PPI) and paravalvular leak (PVL).

01 enero 2018

JACC: CARDIOVASCULAR INTERVENTIONS. Impact of Pre-Existing Prosthesis-Patient Mismatch on Survival Following Aortic Valve-in-Valve Procedures

Philippe Pibarot, Matheus Simonato, Marco Barbanti, Axel Linke, Ran Kornowski, Tanja Rudolph, Mark Spence, Neil Moat, Gabriel Aldea, Marco Mennuni, Alessandro Iadanza, Hafid Amrane, Diego Gaia, Won-Keun Kim, Massimo Napodano, Hardy Baumbach, Ariel Finkelstein, Junjiro Kobayashi, Stephen Brecker, Creighton Don, Alfredo Cerillo, Axel Unbehaun, David Attias, Mohammed Nejjari, Noah Jones, Claudia Fiorina, Didier Tchetche, Raphael Philippart, Konstantinos Spargias, Jose-Maria Hernandez, Azeem Latib and Danny Dvir

Objectives: The aim of this study was to determine whether the association of small label size of the surgical valve with increased mortality after transcatheter valve-in-valve (ViV) implantation is, at least in part, related to pre-existing prosthesis-patient mismatch (PPM) (i.e., a bioprosthesis that is too small in relation to body size).

01 enero 2018

JACC: CARDIOVASCULAR INTERVENTIONS. Prognostic Impact of Left Ventricular Ejection Fraction in Patients With Severe Aortic Stenosis

Tomohiko Taniguchi, Takeshi Morimoto, Hiroki Shiomi, Kenji Ando, Norio Kanamori, Koichiro Murata, Takeshi Kitai, Kazushige Kadota, Chisato Izumi, Kenji Nakatsuma, Tomoki Sasa, Hirotoshi Watanabe, Yasuhide Kuwabara, Takeru Makiyama, Koh Ono, Satoshi Shizuta, Takao Kato, Naritatsu Saito, Kenji Minatoya, Takeshi Kimura, on behalf of the CURRENT AS Registry Investigators, Takeshi Kimura, Tomohiko Taniguchi, Hiroki Shiomi, Naritatsu Saito, Masao Imai, Junichi Tazaki, Toshiaki Toyota, Hirooki Higami, Tetsuma Kawaji, Kenji Ando, Shinichi Shirai, Kengo Kourai, Takeshi Arita, Shiro Miura, Kyohei Yamaji, Takeshi Aoyama, Norio Kanamori, Tomoya Onodera, Koichiro Murata, Yutaka Furukawa, Takeshi Kitai, Kitae Kim, Kazushige Kadota, Yuichi Kawase, Keiichiro Iwasaki, Hiroshi Miyawaki, Ayumi Misao, Akimune Kuwayama, Masanobu Ohya, Takenobu Shimada, Hidewo Amano, Yoshihisa Nakagawa, Chisato Izumi, Makoto Miyake, Masashi Amano, Yusuke Takahashi, Yusuke Yoshikawa, Shunsuke Nishimura, Maiko Kuroda, Manabu Shirotani, Hirokazu Mitsuoka, Shinji Miki, Tetsu Mizoguchi, Masashi Kato, Takafumi Yokomatsu, Akihiro Kushiyama, Hidenori Yaku, Toshimitsu Watanabe, Shunichi Miyazaki, Yutaka Hirano, Mitsuo Matsuda, Shintaro Matsuda, Sachiko Sugioka, Tsukasa Inada, Kazuya Nagao, Naoki Takahashi, Kohei Fukuchi, Tomoyuki Murakami, Hiroshi Mabuchi, Teruki Takeda, Tomoko Sakaguchi, Keiko Maeda, Masayuki Yamaji, Motoyoshi Maenaka, Yutaka Tadano, Hiroki Sakamoto, Yasuyo Takeuchi, Makoto Motooka, Ryusuke Nishikawa, Hiroshi Eizawa, Keiichiro Yamane, Mitsunori Kawato, Minako Kinoshita, Kenji Aida, Takashi Tamura, Mamoru Toyofuku, Kousuke Takahashi, Euihong Ko, Masaharu Akao, Mitsuru Ishii, Nobutoyo Masunaga, Hisashi Ogawa, Moritake Iguchi, Takashi Unoki, Kensuke Takabayashi, Yasuhiro Hamatani, Yugo Yamashita, Moriaki Inoko, Eri Minamino-Muta, Takao Kato, Yoshihiro Himura, Tomoyuki Ikeda, Katsuhisa Ishii, Akihiro Komasa, Yukihito Sato, Kozo Hotta, Shuhei Tsuji, Yuji Hiraoka, Nobuya Higashitani, Ichiro Kouchi, Yoshihiro Kato, Shigeru Ikeguchi, Yasutaka Inuzuka, Soji Nishio, Jyunya Seki, Eiji Shinoda, Miho Yamada, Akira Kawamoto, Chiyo Maeda, Takashi Konishi, Toshikazu Jinnai, Kouji Sogabe, Michiya Tachiiri, Yukiko Matsumura, Chihiro Ota, Shoji Kitaguchi, Yuko Morikami, Ryuzo Sakata, Kenji Minakata, Kenji Minatoya, Michiya Hanyu, Fumio Yamazaki, Tadaaki Koyama, Tatsuhiko Komiya, Kazuo Yamanaka, Noboru Nishiwaki, Hiroyuki Nakajima, Motoaki Ohnaka, Hiroaki Osada, Katsuaki Meshii, Toshihiko Saga, Masahiko Onoe, Shogo Nakayama, Genichi Sakaguchi, Atsushi Iwakura, Kotaro Shiraga, Koji Ueyama, Keiichi Fujiwara, Atsushi Fukumoto, Masaki Park, Junichiro Nishizawa and Mitsuru Kitano

Objectives: The aim of this study was to evaluate the prognostic impact of left ventricular ejection fraction (LVEF) in patients with severe aortic stenosis (AS).

01 enero 2018

JACC: CARDIOVASCULAR INTERVENTIONS. Early Outcomes With the Evolut PRO Repositionable Self-Expanding Transcatheter Aortic Valve With Pericardial Wrap

John K. Forrest, Abeel A. Mangi, Jeffrey J. Popma, Kamal Khabbaz, Michael J. Reardon, Neal S. Kleiman, Steven J. Yakubov, Daniel Watson, Susheel Kodali, Isaac George, Peter Tadros, George L. Zorn III, John Brown, Robert Kipperman, Sara Saul, Hongyan Qiao, Jae K. Oh and Mathew R. Williams

Objectives: This study sought to evaluate the Medtronic Evolut PRO Transcatheter Aortic Valve System in patients with severe symptomatic aortic stenosis.

01 enero 2018

JACC: CARDIOVASCULAR INTERVENTIONS. Multisite Investigation of Outcomes With Implementation of CYP2C19 Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention

Larisa H. Cavallari, Craig R. Lee, Amber L. Beitelshees, Rhonda M. Cooper-DeHoff, Julio D. Duarte, Deepak Voora, Stephen E. Kimmel, Caitrin W. McDonough, Yan Gong, Chintan V. Dave, Victoria M. Pratt, Tameka D. Alestock, R. David Anderson, Jorge Alsip, Amer K. Ardati, Brigitta C. Brott, Lawrence Brown, Supatat Chumnumwat, Michael J. Clare-Salzler, James C. Coons, Joshua C. Denny, Chrisly Dillon, Amanda R. Elsey, Issam S. Hamadeh, Shuko Harada, William B. Hillegass, Lindsay Hines, Richard B. Horenstein, Lucius A. Howell, Linda J.B. Jeng, Mark D. Kelemen, Yee Ming Lee, Oyunbileg Magvanjav, May Montasser, David R. Nelson, Edith A. Nutescu, Devon C. Nwaba, Ruth E. Pakyz, Kathleen Palmer, Josh F. Peterson, Toni I. Pollin, Alison H. Quinn, Shawn W. Robinson, Jamie Schub, Todd C. Skaar, D. Max Smith, Vindhya B. Sriramoju, Petr Starostik, Tomasz P. Stys, James M. Stevenson, Nicholas Varunok, Mark R. Vesely, Dyson T. Wake, Karen E. Weck, Kristin W. Weitzel, Russell A. Wilke, James Willig, Richard Y. Zhao, Rolf P. Kreutz, George A. Stouffer, Philip E. Empey, Nita A. Limdi, Alan R. Shuldiner, Almut G. Winterstein, Julie A. Johnson and on behalf of the IGNITE Network

Objectives: This multicenter pragmatic investigation assessed outcomes following clinical implementation of CYP2C19 genotype–guided antiplatelet therapy after percutaneous coronary intervention (PCI).

01 enero 2017

CATHETERIZATION & CARDIOVASCULAR INTERVENTIONS. Baseline anemia and its impact on midterm outcome after transcatheter aortic valve implantation

Moritz Seiffert MD, Lenard Conradi MD, Andreas Gutwein BSC, Gerhard Schön MSC, Florian Deuschl MD, Niklas Schofer MD, Nina Becker BSC, Johannes Schirmer MD, Hermann Reichenspurner MD, PhD, Stefan Blankenberg MD, Hendrik Treede MD, Ulrich Schäfer MD

Background: Anemia is linked to impaired outcome in patients with cardiovascular diseases. We sought to characterize the impact of baseline anemia on mid-term outcome after transcatheter aortic valve implantation (TAVI).

01 enero 2017

CATHETERIZATION & CARDIOVASCULAR INTERVENTIONS. Transfemoral aortic valve implantation of Edwards SAPIEN 3 without predilatation

Won‐Keun Kim MD, Fabien Praz MD, Johannes Blumenstein MD, Christoph Liebetrau MD, Luise Gaede MD, Arnaud Van Linden MD, Christian Hamm MD, PhD, Thomas Walther MD, PhD, Stephan Windecker MD, PhD, Helge Möllmann MD, PhD

Objectives: The purpose of the present study was to investigate whether transfemoral implantation of the balloon‐expandable Edwards SAPIEN 3 device without prior balloon valvuloplasty is feasible.

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