Intracerebral hemorrhage (ICH) secondary to intravenous and intraarterial revascularization strategies for emergent treatment of acute ischemic stroke is associated with high mortality. ICH from systemic thrombolysis typically occurs within the first 24–36 hours of treatment initiation and is characterized by rapid hematoma development and growth. Pathophysiological mechanisms of revascularization therapy-induced ICH are complex and involve a combination of several distinct processes, including the direct effect of thrombolytic agents, disruption of the blood-brain barrier secondary to ischemia, and direct vessel damage from wire and microcatheter manipulations during endovascular procedures. Several definitions of ICH secondary to thrombolysis currently exist, depending on clinical or radiological characteristics used. Multiple studies have investigated clinical and laboratory risk factors associated with higher rates of ICH in this setting. Neurosurgical Focus. Apr 2012 / Vol. 32 / No. 4 / Page E2. DOI: 10.3171/2012.1.FOCUS11352.
Purpose: To perform a detailed analysis of blinding effi cacy in the Investigational Vertebroplasty Effi cacy and Safety Trial (INVEST) to determine any factors associated with patient unblinding. Radiology: Volume 257: Number 1—October 2010. Copiryght © RSNA, 2010
Purpose: To analyze the clinical and anatomic factors that affect the occurrence and outcome of complications (thromboembolic events and intraoperative rupture in the endovascular treatment of ruptured intracranial aneurysms in a large multicenter series, the CLARITY study (Clinical and Anatomic Results in the Treatment of Ruptured Intracranial Aneurysms). Radiology: Volume 256: Number 3—September 2010. Copiryght © RSNA, 2010
BACKGROUND AND PURPOSE: A number of thrombectomy devices are currently undergoing clinical evaluation; meanwhile, various novel devices are under investigation. The aims of this study were to quantify flow restoration and the particle size distribution of the effluent pursuant to MET in an in vitro occlusion model. Published online before print May 3, 2012, doi: 10.3174/ajnr.A3103. Copyright © 2012 American Society of Neuroradiology
Object: Given the feasibility of curative surgical and endovascular therapy for cerebral dural arteriovenous fistulas (DAVFs), there is a relative paucity of radiosurgical series for these lesions as compared with their arteriovenous malformation counterparts. Neurosurgical Focus. May 2012 / Vol. 32 / No. 5 / Page E18. DOI: 10.3171/2012.1.FOCUS11354.
Background and Purpose—Worldwide, different scales are used to assess the clinical condition on admission after aneurysmal subarachnoid hemorrhage. In addition to the prognostic value, the inter-rater variability should be taken into account when deciding which scale preferably should be used. We assessed the interobserver agreement of the commonly used World Federation of Neurological Surgeons, the Hunt and Hess, and the Prognosis on Admission of Aneurysmal Subarachnoid Hemorrhage scales. Stroke. 2011; 42: 1546-1549 Published online before print April 28, 2011. Copyright © 2011 American Heart Association, Inc. All rights reserved. Print ISSN: 0039-2499. Online ISSN: 1524-4628.
Background and Purpose—We hypothesize that in acute middle cerebral artery stroke, thrombus lengths measured in thin-slice nonenhanced CT images define a limit beyond which systemic thrombolysis will fail to recanalize occluded arteries. Stroke. 2011; 42: 1775-1777 Published online before print April 7, 2011. Copyright © 2011 American Heart Association, Inc. All rights reserved. Print ISSN: 0039-2499. Online ISSN: 1524-4628
Purpose: To explore the lower limits for radiofrequency (RF) power– induced specific absorption rate (SAR) achievable at 1.5 T for brain magnetic resonance (MR) imaging without loss of tissue signal or contrast present in high-SAR clinical imaging in order to create a potentially viable MR method at ultra-low RF power to image tissues containing Materials and Methods: implanted devices. Copyright RSNA 2011. Radiology: Volume 259: Number 2—May 2011. radiology.rsna.org
Context: Although the efficacy of carotid stenting has been established in clinical trials, outcomes of the procedure based on operator experience are less certain in clinical practice. Objective: To assess association between outcomes and 2 measures of operator experience: annual volume and experience at the time of the procedure among new operators who first performed carotid stenting after a national coverage decision by the Centers for Medicare & Medicaid Services (CMS). Copyright ©2011 American Medical Association. All rights reserved. JAMA, September 28, 2011—Vol 306, No. 12
Background and Purpose: Our objective was to evaluate the relationship between cannabis use and ischemic stroke in a young adult population. Stroke. 2011; 42: 1778-1780 Published online before print April 21, 2011. Copyright © 2011 American Heart Association, Inc. All rights reserved. Print ISSN: 0039-2499. Online ISSN: 1524-4628.
Background and Purpose—Chronic deficiencies in regional blood flow lead to cerebral cortical thinning without evidence of gross tissue loss at the same time as potentially negatively impacting on neurological and cognitive performance. This is most pronounced in patients with severe occlusive cerebrovascular disease in whom affected brain areas exhibit “steal physiology,” a paradoxical reduction of cerebral blood flow in response to a global vasodilatory stimulus intended to increase blood flow. We tested whether surgical brain revascularization that eliminates steal physiology can reverse cortical thinning. Stroke. 2011; 42: 1631-1637 Published online before print April 14, 2011. Copyright © 2011 American Heart Association, Inc. All rights reserved. Print ISSN: 0039-2499. Online ISSN: 1524-4628.
Background and Purpose—Fewer than 5% of patients with acute ischemic stroke are currently treated, and there is need for additional treatment options. A novel catheter treatment (NeuroFlo) that increases cerebral blood flow was tested to 14 hours. Stroke. 2011; 42: 1680-1690 Published online before print May 12, 2011. Copyright © 2011 American Heart Association, Inc. All rights reserved. Print ISSN: 0039-2499. Online ISSN: 1524-4628.
BACKGROUND AND PURPOSE: Recently, the use of stents to assist in the coiling and repair of wide-neck aneurysms has been shown to be highly effective; however, the effect of these stents on the RC of the parent vessel has not been quantified. The purpose of this study was to quantify the effect of intracranial stenting on the RC of the implanted artery using 3D datasets. Published online before print April 26, 2012, doi: 10.3174/ajnr.A3062. Copyright © 2012 American Society of Neuroradiology
Purpose: To determine the test characteristics of magnetic resonance (MR) angiography in the assessment of occlusion of aneurysms treated with coil placement. July 2010 Radiology: 256, 209-218. Copiryght © RSNA, 2010
BACKGROUND AND PURPOSE: The progression of atherosclerosis is related to various factors. Although antiplatelet therapy is used for the management of acute ischemic stroke and for the prevention of recurrent stroke, the antiplatelet agent cilostazol may also reduce restenosis after stent implantation in any vessel. This study was performed to assess the impact of cilostazol on plaque progression in the carotid artery contralateral to a stented artery. Published online before print February 9, 2012, doi: 10.3174/ajnr.A2955. Copyright © 2012 American Society of Neuroradiology
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